Overview
Non-cirrhotic portal fibrosis (NCPF) is a chronic liver disease and type of non-cirrhotic portal hypertension (NCPH). Non-cirrhotic portal hypertension (NCPH) is a term used to describe a heterogeneous group of diseases characterized by the presence of portal hypertension with preserved liver structure and function
There are veins which carry blood from the various digestive organs to the liver. When there is an obstruction in the free flow of blood in the liver, it increases the pressure and is known as Non-cirrhotic portal fibrosis This increased blood pressure stresses the blood vessels in the esophagus, stomach, and other digestive organs and results in internal bleeding.
What Causes Non-Cirrhotic Portal Fibrosis?
Cirrhosis is the most common cause of portal hypertension. The cirrhosis could be a result of excessive consumption of alcohol, chronic hepatitis, or thrombosis in the liver vessels. Blood clots in the portal vein are schistosomiasis ( a parasiticinfection) are some other causes of portal hypertension. It is also important to know that in some cases, the causes of this condition remain unknown.